体から除去された血液はまだ免疫力がありますか?


2

血液には白血球(病原体を攻撃する)が含まれています。体から半リットルの血液を取り出し、それにウイルスを移植するとします。その半リットルの血液中の白血球はウイルスを攻撃して抗体を作ることができますか?

4

The usual approach is to use a whole animal such as horses

The results of our research indicate that healthy horses immunized with the SARS-CoV F69 strain can be induced to generate effective, specific and neutralizing antibodies

and to prevent anaphylaxis

Heterogenous antisera used for treatment possibly result in anaphylactoid severe acute side-effects[28]. To avoid the side-effects caused by horse antiserum, IgG against SARS-CoV was digested with pepsin and purified with anion-exchange separations to exclude the immunogenicity of Fc fragments and to retain the special activity of binding the antigen of F(ab')2 fraction. The titers of neutralizing F(ab')2 against SARS-CoV was detected at higher level (1:5120). And approximately 15 g F(ab')2 fragments were obtained from 1 litre antiserum, with the purity above 90%.

https://www.nature.com/articles/aps2005215.pdf